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1

Differentiating SGBS adipocytes respond to PPARγ stimulation, irisin and BMP7 by functional browning and beige characteristics

Klusóczki, Ágnes, Veréb, Zoltán, Vámos, Attila, Fischer-Posovszky, Pamela, Wabitsch, Martin, Bacso, Zsolt, Fésüs, László, Kristóf, Endre

Journal:

Scientific Reports

Year:

2019

Language:

english

File:

PDF, 5.22 MB

english, 2019

2

The Effect of the HIV Protease Inhibitor Ritonavir on Proliferation, Differentiation, Lipogenesis, Gene Expression and Apoptosis of Human Preadipocytes and Adipocytes

Grigem, S., Fischer-Posovszky, P., Debatin, K. M., Loizon, E., Vidal, H., Wabitsch, M.

Journal:

Hormone and Metabolic Research

Year:

2005

Language:

english

File:

PDF, 298 KB

english, 2005

3

A New Missense Mutation in the Leptin Gene Causes Mild Obesity and Hypogonadism without Affecting T Cell Responsiveness

Fischer-Posovszky, Pamela, von Schnurbein, Julia, Moepps, Barbara, Lahr, Georgia, Strauss, Gudrun, Barth, Thomas F., Kassubek, Jan, Mühleder, Hannes, Möller, Peter, Debatin, Klaus-Michael, Gierschik,

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2010

Language:

english

File:

PDF, 302 KB

english, 2010

4

THP-1 Macrophages and SGBS Adipocytes ? A New Human in vitro Model System of Inflamed Adipose Tissue

Keuper, Michaela, Dzyakanchuk, Anna, Amrein, Kurt E., Wabitsch, Martin, Fischer-Posovszky, Pamela

Journal:

Frontiers in Endocrinology

Year:

2011

Language:

english

File:

PDF, 1.06 MB

english, 2011

5

Entwicklung und Funktion des Fettgewebes

P. Fischer-Posovszky, M. Wabitsch

Journal:

Monatsschrift Kinderheilkunde

Year:

2004

Language:

german

File:

PDF, 550 KB

german, 2004

6

Grundlagen der Fettgewebsforschung und Adipozytokine

M. Wabitsch, P. Fischer-Posovszky

Journal:

Gynäkologische Endokrinologie

Year:

2008

Language:

german

File:

PDF, 622 KB

german, 2008

7

LIGHT (TNFSF14) inhibits adipose differentiation without affecting adipocyte metabolism

Tiller, G, Laumen, H, Fischer-Posovszky, P, Finck, A, Skurk, T, Keuper, M, Brinkmann, U, Wabitsch, M, Link, D, Hauner, H

Journal:

International Journal of Obesity

Year:

2010

Language:

english

File:

PDF, 461 KB

english, 2010

8

4-hydroperoxy-cyclophosphamide mediates caspase-independent T-cell apoptosis involving oxidative stress-induced nuclear relocation of mitochondrial apoptogenic factors AIF and EndoG

Strauss, G, Westhoff, M-A, Fischer-Posovszky, P, Fulda, S, Schanbacher, M, Eckhoff, S M, Stahnke, K, Vahsen, N, Kroemer, G, Debatin, K-M

Journal:

Cell Death & Differentiation

Year:

2007

Language:

english

File:

PDF, 613 KB

english, 2007

9

Differential function of Akt1 and Akt2 in human adipocytes

Pamela Fischer-Posovszky, Daniel Tews, Sina Horenburg, Klaus-Michael Debatin, Martin Wabitsch

Journal:

Molecular and Cellular Endocrinology

Year:

2012

Language:

english

File:

PDF, 535 KB

english, 2012

10

Downregulation of FLIP by cycloheximide sensitizes human fat cells to CD95-induced apoptosis

Pamela Fischer-Posovszky, Michaela Keuper, Stella Nagel, Deike Hesse, Annette Schürmann, Klaus-Michael Debatin, Gudrun Strauss, Martin Wabitsch

Journal:

Experimental Cell Research

Year:

2011

Language:

english

File:

PDF, 930 KB

english, 2011

11

Adiponectin expression in humans is dependent on differentiation of adipocytes and down-regulated by humoral serum components of high molecular weight

Antje Körner, Martin Wabitsch, Bertolt Seidel, Pamela Fischer-Posovszky, Antje Berthold, Michael Stumvoll, Matthias Blüher, Jürgen Kratzsch, Wieland Kiess

Journal:

Biochemical and Biophysical Research Communications

Year:

2005

Language:

english

File:

PDF, 349 KB

english, 2005

12

An inflammatory micro-environment promotes human adipocyte apoptosis

Michaela Keuper, Matthias Blüher, Michael R. Schön, Peter Möller, Anna Dzyakanchuk, Kurt Amrein, Klaus-Michael Debatin, Martin Wabitsch, Pamela Fischer-Posovszky

Journal:

Molecular and Cellular Endocrinology

Year:

2011

Language:

english

File:

PDF, 930 KB

english, 2011

13

Resveratrol-Induced Changes of the Human Adipocyte Secretion Profile

Rosenow, Anja, Noben, Jean-Paul, Jocken, Johan, Kallendrusch, Sonja, Fischer-Posovszky, Pamela, Mariman, Edwin C.M., Renes, Johan

Journal:

Journal of Proteome Research

Year:

2012

Language:

english

File:

PDF, 3.75 MB

english, 2012

14

FTO Deficiency Induces UCP-1 Expression and Mitochondrial Uncoupling in Adipocytes

Tews, D., Fischer-Posovszky, P., Fromme, T., Klingenspor, M., Fischer, J., Rüther, U., Marienfeld, R., Barth, T. F., Möller, P., Debatin, K. M., Wabitsch, M.

Journal:

Year:

2013

Language:

english

File:

PDF, 1.19 MB

english, 2013

15

Effects of TWEAK (TNF Superfamily Member 12) on Differentiation, Metabolism, and Secretory Function of Human Primary Preadipocytes and Adipocytes

Tiller, Gabriele, Fischer-Posovszky, Pamela, Laumen, Helmut, Finck, Andreas, Skurk, Thomas, Keuper, Michaela, Brinkmann, Ulrich, Wabitsch, Martin, Link, Dieter, Hauner, Hans

Journal:

Year:

2009

Language:

english

File:

PDF, 262 KB

english, 2009

16

High content analysis of differentiation and cell death in human adipocytes

Doan, Minh X. Q., Sarvari, Anitta K., Fischer-Posovszky, Pamela, Wabitsch, Martin, Balajthy, Zoltan, Fesus, Laszlo, Bacso, Zsolt

Journal:

Cytometry Part A

Year:

2013

Language:

english

File:

PDF, 659 KB

english, 2013

17

Spare mitochondrial respiratory capacity permits human adipocytes to maintain ATP homeostasis under hypoglycemic conditions

Keuper, M., Jastroch, M., Yi, C.-X., Fischer-Posovszky, P., Wabitsch, M., Tschop, M. H., Hofmann, S. M.

Journal:

The FASEB Journal

Year:

2014

Language:

english

File:

PDF, 431 KB

english, 2014

18

Absence of CC chemokine receptors 2a and 2b from human adipose lineage cells

Koenig, Carolin, Fischer-Posovszky, Pamela, Rojewski, Markus T., Tews, Daniel, Schrezenmeier, Hubert, Wabitsch, Martin, Gierschik, Peter, Moepps, Barbara

Journal:

Molecular and Cellular Endocrinology

Year:

2013

Language:

english

File:

PDF, 1.47 MB

english, 2013

19

Up-regulation of Bcl-2 during adipogenesis mediates apoptosis resistance in human adipocytes

Nagel, Stella A., Keuper, Michaela, Zagotta, Ivana, Enlund, Eveliina, Ruperez, Azahara Iris, Debatin, Klaus-Michael, Wabitsch, Martin, Fischer-Posovszky, Pamela

Journal:

Molecular and Cellular Endocrinology

Year:

2014

Language:

english

File:

PDF, 1.15 MB

english, 2014

20

T-lymphocyte Infiltration in Visceral Adipose Tissue: A Primary Event in Adipose Tissue Inflammation and the Development of Obesity-Mediated Insulin Resistance

Kintscher, U., Hartge, M., Hess, K., Foryst-Ludwig, A., Clemenz, M., Wabitsch, M., Fischer-Posovszky, P., Barth, T. F.E., Dragun, D., Skurk, T., Hauner, H., Bluher, M., Unger, T., Wolf, A.-M., Knippsc

Journal:

Arteriosclerosis Thrombosis and Vascular Biology

Year:

2008

Language:

english

File:

PDF, 1.04 MB

english, 2008

21

Comparative gene array analysis of progenitor cells from human paired deep neck and subcutaneous adipose tissue

Tews, D., Schwar, V., Scheithauer, M., Weber, T., Fromme, T., Klingenspor, M., Barth, T.F., Möller, P., Holzmann, K., Debatin, K.M., Fischer-Posovszky, P., Wabitsch, M.

Journal:

Molecular and Cellular Endocrinology

Year:

2014

Language:

english

File:

PDF, 1.86 MB

english, 2014

22

Biologically Inactive Leptin and Early-Onset Extreme Obesity

Wabitsch, Martin, Funcke, Jan-Bernd, Lennerz, Belinda, Kuhnle-Krahl, Ursula, Lahr, Georgia, Debatin, Klaus-Michael, Vatter, Petra, Gierschik, Peter, Moepps, Barbara, Fischer-Posovszky, Pamela

Journal:

New England Journal of Medicine

Year:

2015

Language:

english

File:

PDF, 622 KB

english, 2015

23

TRAIL (TNF-related apoptosis-inducing ligand) regulates adipocyte metabolism by caspase-mediated cleavage of PPARgamma

Keuper, M, Wernstedt Asterholm, I, Scherer, P E, Westhoff, M-A, Möller, P, Debatin, K-M, Strauss, G, Wabitsch, M, Fischer-Posovszky, P

Journal:

Cell Death and Disease

Year:

2013

Language:

english

File:

PDF, 1.94 MB

english, 2013

24

Toll-like receptor 5 in obesity: The role of gut microbiota and adipose tissue inflammation

Pekkala, Satu, Munukka, Eveliina, Kong, Lingjia, Pöllänen, Eija, Autio, Reija, Roos, Christophe, Wiklund, Petri, Fischer-Posovszky, Pamela, Wabitsch, Martin, Alen, Markku, Huovinen, Pentti, Cheng, Sul

Journal:

Year:

2015

Language:

english

File:

PDF, 567 KB

english, 2015

25

Gene expression levels of Casein kinase 1 (CK1) isoforms are correlated to adiponectin levels in adipose tissue of morbid obese patients and site-specific phosphorylation mediated by CK1 influences multimerization of adiponectin

Xu, Pengfei, Fischer-Posovszky, Pamela, Bischof, Joachim, Radermacher, Peter, Wabitsch, Martin, Henne-Bruns, Doris, Wolf, Anna-Maria, Hillenbrand, Andreas, Knippschild, Uwe

Journal:

Molecular and Cellular Endocrinology

Year:

2015

Language:

english

File:

PDF, 3.21 MB

english, 2015

26

RBP4: a controversial adipokine

Kotnik, P., Fischer-Posovszky, P., Wabitsch, M.

Journal:

European Journal of Endocrinology

Year:

2011

Language:

english

File:

PDF, 181 KB

english, 2011

27

TNF-related apoptosis-inducing ligand promotes human preadipocyte proliferation via ERK1/2 activation

Funcke, J.-B., Zoller, V., El Hay, M. A., Debatin, K.-M., Wabitsch, M., Fischer-Posovszky, P.

Journal:

The FASEB Journal

Year:

2015

Language:

english

File:

PDF, 1.39 MB

english, 2015

28

Identification of a novel proapoptotic function of resveratrol in fat cells: SIRT1-independent sensitization to TRAIL-induced apoptosis

Mader, I., Wabitsch, M., Debatin, K. M., Fischer-Posovszky, P., Fulda, S.

Journal:

The FASEB Journal

Year:

2010

Language:

english

File:

PDF, 1.26 MB

english, 2010

29

Obesity and inflammation: reduced cytokine expression due to resveratrol in a human in vitro model of inflamed adipose tissue

Zagotta, Ivana, Dimova, Elitsa Y., Debatin, Klaus-Michael, Wabitsch, Martin, Kietzmann, Thomas, Fischer-Posovszky, Pamela

Journal:

Frontiers in Pharmacology

Year:

2015

Language:

english

File:

PDF, 2.06 MB

english, 2015

30

Human SGBS Cells – a Unique Tool for Studies of Human Fat Cell Biology

Fischer-Posovszky, Pamela, Newell, Felicity S., Wabitsch, Martin, Tornqvist, Hans E.

Journal:

Year:

2008

Language:

english

File:

PDF, 271 KB

english, 2008

31

Pioglitazone reduces inflammatory responses of human adipocytes to factors secreted by monocytes/macrophages

Permana, P. A., Zhang, W., Wabitsch, M., Fischer-Posovszky, P., Duckworth, W. C., Reaven, P. D.

Journal:

AJP Endocrinology and Metabolism

Year:

2009

Language:

english

File:

PDF, 741 KB

english, 2009

32

Resveratrol regulates human adipocyte number and function in a Sirt1-dependent manner

Fischer-Posovszky, P., Kukulus, V., Tews, D., Unterkircher, T., Debatin, K.-M., Fulda, S., Wabitsch, M.

Journal:

American Journal of Clinical Nutrition

Year:

2010

Language:

english

File:

PDF, 828 KB

english, 2010

33

Targeted Deletion of Adipocytes by Apoptosis Leads to Adipose Tissue Recruitment of Alternatively Activated M2 Macrophages

Fischer-Posovszky, Pamela, Wang, Qiong A., Asterholm, Ingrid Wernstedt, Rutkowski, Joseph M., Scherer, Philipp E.

Journal:

Year:

2011

Language:

english

File:

PDF, 1.39 MB

english, 2011

34

Regulation of FTO and FTM Expression During Human Preadipocyte Differentiation

Tews, D., Fischer-Posovszky, P., Wabitsch, M.

Journal:

Hormone and Metabolic Research

Year:

2011

Language:

english

File:

PDF, 332 KB

english, 2011

35

Endocrinology of Adipose Tissue - An Update

Fischer-Posovszky, P., Wabitsch, M., Hochberg, Z.

Journal:

Hormone and Metabolic Research

Year:

2007

Language:

english

File:

PDF, 184 KB

english, 2007

36

Conjugated Linoleic Acids Promote Human Fat Cell Apoptosis

Fischer-Posovszky, P., Kukulus, V., Zulet, M., Debatin, K., Wabitsch, M.

Journal:

Hormone and Metabolic Research

Year:

2007

Language:

english

File:

PDF, 184 KB

english, 2007

37

FTO – Friend or Foe?

Tews, D., Fischer-Posovszky, P., Wabitsch, M.

Journal:

Hormone and Metabolic Research

Year:

2010

Language:

english

File:

PDF, 250 KB

english, 2010

38

Influence of Sex Hormones on Adiponectin Expression in Human Adipocytes

Horenburg, S., Fischer-Posovszky, P., Debatin, K.-M., Wabitsch, M.

Journal:

Hormone and Metabolic Research

Year:

2008

Language:

english

File:

PDF, 395 KB

english, 2008

39

Role of CD95-Mediated Adipocyte Loss in Autoimmune Lipodystrophy

Fischer-Posovszky, Pamela, Hebestreit, Helge, Hofmann, Albert K., Strauss, Gudrun, Möller, Peter, Debatin, Klaus-Michael, Wabitsch, Martin

Journal:

Journal of Clinical Endocrinology & Metabolism

Year:

2006

Language:

english

File:

PDF, 472 KB

english, 2006

40

Lipodystrophien - Übersicht, Stand der Forschung, Klassifikation, neue Therapien -

Fischer-Posovszky, Pamela, Debatin, K.-M., Wabitsch, M.

Journal:

Klinische Pädiatrie

Year:

2002

Language:

german

File:

PDF, 64 KB

german, 2002

41

Inhibition of Death-Receptor Mediated Apoptosis in Human Adipocytes by the Insulin-Like Growth Factor I (IGF-I)/IGF-I Receptor Autocrine Circuit

Fischer-Posovszky, Pamela, Tornqvist, Hans, Debatin, Klaus-Michael, Wabitsch, Martin

Journal:

Year:

2004

Language:

english

File:

PDF, 551 KB

english, 2004

42

MicroRNA-192* impairs adipocyte triglyceride storage

Mysore, Raghavendra, Zhou, You, Sädevirta, Sanja, Savolainen-Peltonen, Hanna, Nidhina Haridas, P.A., Soronen, Jarkko, Leivonen, Marja, Sarin, Antti-Pekka, Fischer-Posovszky, Pamela, Wabitsch, Martin,

Journal:

Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids

Year:

2016

Language:

english

File:

PDF, 1.68 MB

english, 2016

43

Resveratrol inhibits lipogenesis of 3T3-L1 and SGBS cells by inhibition of insulin signaling and mitochondrial mass increase

Li, Shuijie, Bouzar, Célia, Cottet-Rousselle, Cécile, Zagotta, Ivana, Lamarche, Frédéric, Wabitsch, Martin, Tokarska-Schlattner, Malgorzata, Fischer-Posovszky, Pamela, Schlattner, Uwe, Rousseau, Denis

Journal:

Biochimica et Biophysica Acta (BBA) - Bioenergetics

Year:

2016

Language:

english

File:

PDF, 2.19 MB

english, 2016

44

miR-125b affects mitochondrial biogenesis and impairs brite adipocyte formation and function

Giroud, Maude, Pisani, Didier F., Karbiener, Michael, Barquissau, Valentin, Ghandour, Rayane A., Tews, Daniel, Fischer-Posovszky, Pamela, Chambard, Jean-Claude, Knippschild, Uwe, Niemi, Tarja, Taitton

Journal:

Molecular Metabolism

Year:

2016

Language:

english

File:

PDF, 2.54 MB

english, 2016

45

Physiologische Relevanz des braunen Fettgewebes beim Menschen

Tews, D., Fischer-Posovszky, P., Debatin, K. M., Beer, A. J., Wabitsch, M.

Journal:

Monatsschrift Kinderheilkunde

Year:

2017

Language:

german

File:

PDF, 2.00 MB

german, 2017

46

Functional Significance and Predictive Value of MicroRNAs in Pediatric Obesity: Tiny Molecules with Huge Impact?

Fischer-Posovszky, Pamela, Roos, Julian, Kotnik, Primoz, Battelino, Tadej, Inzaghi, Elena, Nobili, Valerio, Cianfarani, Stefano, Wabitsch, Martin

Journal:

Hormone Research in Paediatrics

Year:

2016

Language:

english

File:

PDF, 939 KB

english, 2016

47

TRAIL (TNF-related apoptosis-inducing ligand) inhibits human adipocyte differentiation via caspase-mediated downregulation of adipogenic transcription factors

Zoller, Verena, Funcke, Jan-Bernd, Keuper, Michaela, Abd El Hay, Muad, Debatin, Klaus-Michael, Wabitsch, Martin, Fischer-Posovszky, Pamela

Journal:

Cell Death and Disease

Year:

2016

Language:

english

File:

PDF, 1.56 MB

english, 2016

48

Clozapine modifies the differentiation program of human adipocytes inducing browning

Kristóf, E, Doan-Xuan, Q-M, Sárvári, A K, Klusóczki, Á, Fischer-Posovszky, P, Wabitsch, M, Bacso, Z, Bai, P, Balajthy, Z, Fésüs, L

Journal:

Translational Psychiatry

Year:

2016

Language:

english

File:

PDF, 3.53 MB

english, 2016

49

miR-146a-mediated suppression of the inflammatory response in human adipocytes

Roos, Julian, Enlund, Eveliina, Funcke, Jan-Bernd, Tews, Daniel, Holzmann, Karlheinz, Debatin, Klaus-Michael, Wabitsch, Martin, Fischer-Posovszky, Pamela

Journal:

Scientific Reports

Year:

2016

Language:

english

File:

PDF, 1.32 MB

english, 2016

50

Teneurin-2 (TENM2) deficiency induces UCP1 expression in differentiating human fat cells

Tews, D., Fromme, T., Keuper, M., Hofmann, S.M., Debatin, K.M., Klingenspor, M., Wabitsch, M., Fischer-Posovszky, P.

Journal:

Molecular and Cellular Endocrinology

Year:

2017

Language:

english

File:

PDF, 1.41 MB

english, 2017

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